![]() Alligator Snapping Turtle: 1,000 PSIĪlligator Snapping Turtle Bite Force : 1,000Īlligator Snapping Turtle Bite Force : 70 If you are stung by a Blue-ringed octopus, seek medical attention immediately. Therefore, it is important to be aware of the Blue-ringed octopus and to avoid contact with them if possible. There is no antivenom available for the Blue-ringed octopus, so treatment for its bite focuses on life support and the management of symptoms. Their venom contains tetrodotoxin, a powerful neurotoxin that can cause paralysis and death. Blue Ringed Octopusĭespite their small size (they are typically only a few inches long), Blue-ringed octopuses are extremely dangerous to humans. They are found in the tide pools and coral reefs of the Pacific and Indian Oceans, and they are known for their striking blue rings that appear when they feel threatened or are hunting prey. The Blue-ringed octopus is one of the world’s most venomous marine animals. While most octopus don’t attack humans, the Blue ringed Octopus is an exception. Some Octopus, are not dangerous because of their suction, but due to their venom they inject in their catch. But if you ever find yourself in a wrestling match with an octopus, watch out for that parrot-like beak! It may be small, but it’s definitely mighty. Octopus Bite Force : 49 Octopus Bite Force PSI: A Giant Octopus in Japans Toyama Bay bites with max 700 PSIĭid you know that an octopus has a bite force of up to 700 pounds per square inch (psi)? That’s stronger than a lion’s jaw! Imagine getting chomped on by one of these cephalopods – it would be like getting hit by a hydraulic press! Thankfully, octopuses are not known to attack humans unprovoked. So while their biting strength is still terrifying on its own accord, it’s the whole package that makes this marine animal nothing to sneeze at, even though it doesn’t have one of the strongest bite force in the ocean. On the other hand, the Great White essentially owns a personal set of high-quality, sharpened razor blades. For example, a hippo’s biting force may seem extreme for a herbivore, but we have to remember that hippos don’t have sharp teeth. These sharks simply don’t need to have as massive a biting force as the other animals. That being said, a Great White Shark’s bite force of 625 PSI compared to a saltwater alligator may not sound impressive, but it’s no joke from a feeble human standpoint. Let’s also consider how many large, sharp teeth a Great White Shark has: about 50, in multiple rows. First, let’s recall the average human’s bite force: 162 PSI. The Great White might not seem so impressive. It has the strongest bite of all living fish today, comparatively. This bite force, along with a set of super-sharp teeth, has made the piranha infamous and feared. Put it into perspective this way: if the alligator were to be shrunk down to the same size, the piranha’s bite force would be almost three times greater than the alligator. That force measures far beyond the typical standard in terms of body weight, making this piranha a truly unexpected animal. 51 cm) long, it has remarkable jaw strength, measuring as much as 455 PSI. Though this nasty fish is only about 20 inches (ca. However, the Black Piranha is undoubtedly an exception to this rule. In most cases, you can expect the strength of an animal’s jaw to be proportionate to its size. That’s more than enough force to crush the shell of a crab or even the armor of a sperm whale! Black Piranha: 455 PSI The Colossal Squid is an elusive creature that lurks in the depths of the Southern Ocean, and it has a bite force that would make even Jaws blush! According to scientists who have studied these giant cephalopods, the Colossal Squid has a beak that can exert a jaw pressure of over 100 pounds per square inch (psi). Colossal Squid: 100 PSIĬolossal Squid Bite Force : 7 The Colossal Squid. In no particular order, check out these marine animals with powerful bites that certainly pack a punch. To put things into focus for you here, we’d like to point out that the average strength of a human bite is about 162 pounds (ca. ![]() Top 12 Marine Animals with the Strongest Bite Force in the Ocean A Few Other strong biting Animals worth mentioning that come close to the Marine Animals with the strongest bite force in the ocean.The Killer Whale has the strongest Bite Force in the Ocean: 19,000 PSI.Top 12 Marine Animals with the Strongest Bite Force in the Ocean.Strongest Bite Force in the Ocean: 12 Madly Strong Marine Animals Whether it’s an effective way to catch dinner or merely a means of self-defense, the top 10 marine animals with the most forceful bites all have some pretty cool features that we’re going to highlight today. Our fascinating list of extreme marine biters consists of hundreds of teeth, thousands of kilograms of power, and unique muscle structures from both fresh and saltwater habitats. ![]()
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![]() As a competitive game matches can be created quickly in succession and combos are formed through the removed panels or by the new ones that fill up the board from the top. It is not necessarily the player with the most points who wins, as various items can be equipped that influence the statistics and abilities. Players need to create matches to build up attack and defense for that sequence. The other player's progress is not visible while playing, but when time is up an animated sequence is shown where the winner is determined. Regular battles are played in real-time against other players worldwide who start with the same lay-out and usually the same time limit. Each character has different types of skills for matches. A match of five triggers a short 'fever time' where all scores count for twice the amount. Matches of four provide special effects such as sabotaging the other player by putting certain panels in cages that need to be tapped, removing entire rows or columns, re-arranging the panels into a favorable lay-out or removing all panels of a single type. Each panel has a different kind of effect, providing attack power, adding to defense etc. Matches of three identical panels or more are created by swapping one horizontally or vertically. The game uses a classic match-three board design for the battles with different panels (icons). An island is divided into different areas and to complete an area an AI-controlled Pig needs to be defeated. ![]() By winning battles experience is gained to level up, earn a currency and acquire new items. The ship visits different islands with real-time battles against human players from around the world. Starting with Red as the captain of a ship, different characters such as Bomb, Chuck, Matilda, Mighty Eagle, Stella, Terrence and The Blues can be unlocked to join as crew and playable characters. ![]() The game uses many elements such as the battle mechanics, lay-out and PvP matches from developer Kiteretsu's earlier game Zookeeper Battle. Continued abuse of our services will cause your IP address to be blocked indefinitely.Angry Birds: Fight! is a match-three puzzle game set in the Angry Birds universe. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. ![]() If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior.
![]() The Duke University Health System Administrative Fellowship Programs will conduct final round "on-site" interviews virtually for the 2024 – 2026 fellowship cycle.We use cookies and similar tools that are necessary to enable you to make purchases, to enhance your shopping experiences and to provide our services, as detailed in our Cookie Notice. Subject Line: ApplicantLastName_ApplicantFirstName LORĭPC: How will Duke University Health System Fellowships conduct "on-site" final round interviews? Yes, please instruct your recommenders to submit to the following emails: Can my recommenders submit their letters separately? Do Duke University Health System Administrative Fellowship Programs host webinars? Please be sure to review the submission instructions carefully for each program, as requirements may vary. Letters of recommendation should be addressed to the respective organization's Administrative Fellowship Selection Committee.Įx. DUH Administrative Fellowship Selection Committee Can I apply for multiple Duke University Health System Administrative Fellowship Programs? To whom should I address my letters of recommendation? Open and close dates are subject to change each year. Please Note: The DUHS Administrative Fellowship programs are not aligned with NCAF deadlines. The application deadline for the 2024-2026 cycle is Tuesday, September 5th, 2023 at 5:00 PM Eastern Time. When will the new application be posted?įellowship applications are updated in July each year. Fellows selected for any program must be prepared to commit to the full two years. ![]() However, applicants should be mindful that all Administrative Fellowship Programs are two-year commitments. If my graduate program requires a year-long residency after completion of coursework, am I still eligible to apply even though I do not yet have my degree?Īpplicants who have completed all coursework are eligible to apply to the program. ![]() At this time, Duke does not sponsor international visas. Do Duke University Health System Administrative Fellowship Programs sponsor international visas? More information about benefits can be found by visiting our HR Website. Fellows are eligible for the benefits package offered to full-time salaried employees of Duke University Health System. What level of salary and benefits do fellows receive?įellows are provided a competitive salary and full benefits each year of the program. Keith Stover, Chief Operating Officer of the Patient Revenue Management Organization, serves as preceptor for the PRMO Administrative Fellowship.Įlizabeth Long, Chief Operating Officer of Duke Primary Care, serves as preceptor for the DPC Administrative Fellowship.ĭev Sangvai, MD, President of Duke Regional Hospital, and Dexter Nolley, Chief Human Resouces Officer of Duke Regional Hospital, serve as preceptors for the Duke Regional Hospital Administrative Fellowship. Simon Curtis, Vice President of Ambulatory Services and Access of Duke Health Integrated Practice, serves as the preceptor for the DHIP Administrative Fellowship. Mary Martin, Chief Operating Officer and Interim President of Duke University Hospital, serves as the preceptor for the DUH Administrative Fellowship. Who are the preceptors for the Duke University Health System Administrative Fellowship Programs? The DRH Administrative Fellowship Program selects one fellow every other year. The DPC Administrative Fellowship Program selects one fellow each year. The PRMO Administrative Fellowship Program selects one to three fellows each year. The DHIP Administrative Fellowship Program selects two fellows each year. The DUH Administrative Fellowship Program selects two fellows each year. How many fellows does Duke typically select? ![]() How long are each of the Duke University Health System Administrative Fellowship Programs?Īll of the Duke fellowship programs are two years. ![]() ![]() ![]() You go to the jewelry section and ask the person behind the counter if they perform the service. Walmart: You might be surprised but some Walmart’s can change your battery for you. Other Alternatives for Watch Battery Replacement Near Me They don’t always advertise the service, but it’s worth asking because many will do it and only charge you for the battery and not for labor. You might be surprised, but the workers there normally have tools to open a watch and replace a battery. Watch Retail Stores: These stores can usually be found at a mall and they sell a few hundred different brands of watches. ![]() If you have a rare or unique timepiece this may be your best option for a battery swap out. They will carry a wide array of watch batteries and be very knowledgeable about almost all brands. Watch Repair Shops: These stores specialize in repair watches and battery replacement is an easy task for them on most watches. They often have a specialist on hand who has the tools to take your watch apart and replace the battery. Jewelry Stores: While these jewelry stores are popular for selling rings, necklaces, and earrings, they also do minor work on men’s and women’s watches. There are typically three types of local stores that can replace a watch battery for you and chances are you will find one of these near you that can help you fix it. What Stores Provide Watch Battery Replacement Near Me?Ĭhanging the battery is one of the most routine requested repairs in the industry. ![]() ![]() ![]() I think that person might have to be drawn in white or gray to stand out from the blue sky. I still haven’t figured out what I’m going to do with my person swinging from the tree branches. Overall, I think it looks sort of strange. My third issue is that in order for the people on the hill to show up, I had to make the sky behind them lighter, which meant having to change colors horizontally and vertically. I wanted the sky to change from blue to purple, but it turns out that the blue-purple blended area is darker than just the straight blue, which makes it go from lighter to darker to lighter. I’m also not a fan of the way the colors blended. The colors still blend pretty well, and then those awful lines wouldn’t be there. If I were to try a sky again like this, I would definitely make sure to color all different directions like I did for the pupil of my giant eye-moon. The thing that bothers me the most is the fact that you can see the lines of the colored pencils. I’ve actually had quite a few problems with it. I’m not a fan of the day the sky turned out. There are definitely some aspects that I’m not thrilled about, but I like the idea/style of the piece and I think it’s a good starting point. I’ve assembled a collage of the progress so far. I’ve been working on a larger abstract drawing. =) Also, I dropped off my art for the Deviant Art show to benefit A Rotta Love today. If you like my art, please check out my personal website here or my profile here to order prints. Now I have something fun to look forward to. I’m glad I put all these images together to give me this idea. While inserting the photos into my post here, I actually came up with an idea for an abstract dog that would fit this style. ![]() It wouldn’t be so bad if I had more time for my art, but since I only have an hour or so a day, and I don’t draw every day, those 7 – 15 hours turn into 2 – 3 weeks of time. With colored pencils, I spend like 7 – 15 hours on a work the size of a normal piece of printing paper. If something didn’t work out, it wouldn’t be a total loss, not a lot of time invested. Being a painter would allow for so much more experimentation with style and colors. I wish paintings weren’t so messy because they are exponentially faster than colored pencils. ![]() I’ve also been doing a bit of browsing the internet, just investigating other animal art and I think I might try some paintings here and there. I still have all the grand ideas mentioned in previous posts, but I’ve decided I better go out of my way to incorporate psychedelic art to help the poor shelter dogs! I do have drawings that I have already started, which I fully intend to finish first, but when they are finished, the psychedelic art will begin. I wish more people cared about the dogs and the animals than about psychedelic stuff, but if that’s what people want, I can take the hint. I find this partially amusing, and partially a little sad. I’ve written mostly about art, which includes a lot of dog talk as well since most of my art revolves around dogs, but when I checked the search terms, I discovered that most people find my blog by searching for stuff that’s psychedelic. I’m not complaining, but I was a bit curious as to why. It surprised me quite a bit to find that after an 8 month hiatus my viewership had gone up. Ever since I returned to this blog I have been checking the statistics and all that good stuff. ![]() ![]() While the various client applications look rather different, they offer the most of the same features: Windows and Android users get a bit of flexibility. You can have up to ten simultaneous connections to your account at given time. These are all within 1.5MB/s of our most recent non-VPN'd reference scores and compare well to the performance of rival providers. In the past 12 months, we've seen download speeds of over 10MB/s from European endpoints. In our latest tests, we saw typical HTTP transfer speeds of 8.68MB/s (69.44Mbit/s) from UK endpoints, 8MB/s in the Netherlands and 6MB/s in the US. (Performance tests can only ever represent a snapshot from a single moment in time and can fluctuate both up and down.) We tested performance from endpoints in the US, UK and the Netherlands, transferring data from servers in the same countries. We not collect and/or store any other user information.ĭownload APK (30.73 MB) PIA VPN 3.22.2 for Androidĭownload APK (30.27 MB) PIA VPN 3.18.0 for Androidĭownload APK (30.23 MB) PIA VPN 3.17.0 for Androidĭownload APK (30.43 MB) PIA VPN 3.16.0 for Androidĭownload APK (30.4 MB) PIA VPN 3.13.0 for Androidĭownload APK (29.76 MB) PIA VPN 3.10.The service provides endpoints in 52 locations across 32 countries and currently has 3341 active VPN and web proxy servers. During signups, we also collect user-email. This application only send username and encrypted passwords to our servers as part of using this app. Earlier versions of Android (before 6.0) will incorrectly report that we need this at all times. The camera is used only when you scan a QR code, nowhere else. Why does the app need camera permissions? 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This news release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Safe Harbor Statement under the Private Securities Litigation Reform Act: Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.įor more information, please visit or follow us on Twitter To be added to the Company's email list and receive news directly, please visit. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. In addition, we believe C3 inhibition has interesting potential, as it is upstream of C5 in the complement cascade."ĪROC3-1001 ( NCT05083364) is a Phase 1/2, placebo controlled, dose-escalating study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ARO-C3 in up to 42 adult healthy volunteers (Part 1), and up to 42 adult patients with paroxysmal nocturnal hemoglobinuria (PNH) or with complement-mediated renal disease (Part 2).Īrrowhead Pharmaceuticals develops medicines that treat intractable diseases by silencing the genes that cause them. "Substantial unmet medical need remains in the treatment of multiple complement mediated diseases, including IgA nephropathy, C3 glomerulopathy, paroxysmal nocturnal hemoglobinuria, and additional renal and hematologic indications, despite the availability of approved complement C5 inhibitors that have significantly improved treatment. These data in healthy volunteers provide us with further confidence as we begin Part 2 of the study, which includes patients with various complement mediated diseases," said James Hamilton, M.D., MBA, chief of discovery and translational medicine at Arrowhead. "ARO-C3 has achieved encouraging results in Part 1 of this Phase 1/2 clinical study, including a mean reduction of 88% in C3 and 91% in AH50 at the highest dose tested. Most common adverse events include headache, COVID-19, generally mild injection site reactions, and seasonal allergy No dose limiting toxicity, serious or severe adverse events, or study discontinuation due to adverse events Overall, no clinically significant laboratory findings or patterns of adverse changes in any clinical laboratory parameters In Part 1 of AROC3-1001, ARO-C3 interim results included:Ī dose-dependent reduction in serum C3, with 88% mean reduction at highest dose testedĪ dose-dependent reduction in AH50, a marker of alternative complement pathway hemolytic activity, with 91% mean reduction at highest dose testedĭuration of pharmacologic effect supportive of quarterly or less frequent subcutaneous dose administration Dosing in Part 2 of the Phase 1/2 study is expected to begin in the first half of 2023. The company plans to present additional results at an upcoming complement-focused medical meeting. (NASDAQ: ARWR) today announced interim results from Part 1 of AROC3-1001, an ongoing Phase 1/2 clinical study of ARO-C3, the company’s investigational RNA interference (RNAi) therapeutic designed to reduce production of complement component 3 (C3) as a potential therapy for various complement mediated diseases. PASADENA, Calif., February 28, 2023-( BUSINESS WIRE)-Arrowhead Pharmaceuticals Inc. Achieved Mean Reductions of 88% in C3 and 91% in AH50 ![]() ![]() ![]() Why You Should Use Our Tiktok Video Downloader? Tiktok is constantly improving based on user experience and feedback. TikTok is available on the Android and iOS. Tiktok video is a great way to showcase creativity and offer an opportunity to reach a large audience. It’s similar to other well known short form video platforms like youtube and Instagram. Users have the opportunity to connect with the largest audience across different categories such as entertainment, education, technology. 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The Freezing and Boiling points are the temperatures at which water freezes and boils on Earth, and the triple point shows at what temperature and pressure water can exist as a solid, liquid, and gas at the same time. ![]() Phase diagram for water shows what phase water has at different temperatures and pressures. Check out the real-life phase diagram of water from Wikipedia as an example, pictured below. Our phase diagrams, which show a material’s state at different temperatures and pressures, are based on data taken in labs as well as geological and astrophysical models of planets. A material’s phase will be simulated based on its temperature and pressure using something called a phase diagram. In our new system, all new materials can exist inside of, on the surface of, or in the atmosphere of a planet. The Liquid Depth Data View shows the depth and location of the methane lakes. Using New Materials for Simulation Titan with realistic lakes of liquid methane in turquoise at its poles. Want to know the freezing point of carbon dioxide or see how fast it’s evaporating on your custom planet? We’ll simulate it in real time. Many, like oxygen and carbon dioxide, will also be necessary for life simulation.Įach material has all the properties described above, and they will update in real-time according to the conditions on the planet (though iron and silicate will only exist inside planets and won’t have customizable colors). ![]() These are the materials necessary to simulate the most interesting internal, liquid, and atmospheric properties of most objects in our Solar System. Our new composition system has 12 materials: iron, silicate, water, hydrogen, helium, carbon dioxide, oxygen, sulfur dioxide, methane, nitrogen, argon, and ammonia. Liquid and solid density, heat of fusion, and heat of vaporization - to determine how fast water flows, evaporates, and freezes on planet surfaces.Mass of the material in each phase (solid, liquid, or gas).Melting point - temperature where a material changes from a solid to a liquid.Boiling point - temperature where a material changes from a liquid to a gas.Water, the only material currently simulated across an object’s surface, has some additional properties Used to create clouds of evaporating gas called volatiles. Molecular weight - average mass of a molecule of the material.Used to determine the Surface Heat Capacity of a planet. Thermal capacity - energy required to increase the material’s temperature by one degree.Density - to compute an object’s mass and radius and determine where materials are within a planet (for example, iron is the densest so it's at the core).Universe Sandbox’s current composition system uses four materials (iron, silicate, water, and hydrogen) each with a set of physical properties including This feature and interface are a work in progress. Material Properties in Universe Sandbox The Composition tab shows material properties, including total mass, the percentage and mass in each phase (solid, liquid, and gas), and more. Learn how to opt-in to a preview version on Steam: Try the Terraforming | Update 34 preview right now!Įight new materials and our new composition system are now available for testing and feedback. Our new system will allow you to realistically simulate planet surfaces and atmospheres, accurately terraform planets, and more. However, our current composition system is too simple to simulate phenomena like lakes of liquid methane on Saturn’s moon Titan. Every planet in Universe Sandbox is simulated with a combination of materials, like iron and water, that are used to compute properties like planet radius and water flow. ![]() Our new composition system, including eight new materials, like oxygen and methane, is still in active development and has not been released, but you can opt-in to a preview version now on Steam. These materials are transferred to the Moon's surface, forming lakes that flow together and eventually evaporate to create an atmosphere. The Moon is bombarded with asteroids made of carbon dioxide, sulfur dioxide, methane, and water. ![]() ![]() ![]() If you decide to continue to use H2, please be sure to back up the database file regularly. For production deployments, we highly recommend using Postgres, MySQL, or MariaDB instead. T19:41:56+01:00 WARN metabase.db WARNING: Using Metabase with an H2 application database is not recommended for production deployments. Please sit tight, this may take a minute. T19:41:56+01:00 INFO re Setting up and migrating Metabase DB. ![]() T19:41:56+01:00 INFO Registered driver :mysql (parents: ) It will take you to that log analytic workspace resource. Click on the configured Log analytics workspace. T19:41:56+01:00 INFO Registered driver :h2 (parents: ) So, to access your Application gateway access logs, follow the below steps: Go to the Application gateway resource and under Monitoring, select Diagnostic settings. T19:41:56+01:00 INFO Registered driver :sqlserver (parents: ) ![]() T19:41:56+01:00 DEBUG -loaded-driver Registering lazy loading driver :sqlserver. T19:41:56+01:00 INFO Registered driver :bigquery (parents: ) T19:41:55+01:00 INFO rver Launching Embedded Jetty Webserver with config: T19:41:55+01:00 INFO re Starting Metabase in STANDALONE mode Proxy_set_header X-Forwarded-For $proxy_add_x_forwarded_for Ĭhecking the Metabase log when it crashes, I see that it starts again loading all from the beginning Proxy_set_header X-Forwarded-Server $host Ssl_certificate_key /etc/letsencrypt/live//privkey.pem Ssl_certificate /etc/letsencrypt/live//fullchain.pem My nf located in /etc/nginx/sites-available/nf : "java.vm.name": "OpenJDK 64-Bit Server VM", Can this issue be related to actual H2 database? For now I'm using the H2 database, but I plan to migrate to Postgresql. ![]() |
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